Welcome to CBB

The Center for Biocatalysis and Bioprocessing (CBB) is a microbial biomanufacturing and research facility that bridges the gap between laboratory discovery and commercial-scale bioprocessing solutions. Located at the University of Iowa, CBB offers microbial fermentation, recombinant protein expression, and downstream protein purification services for a wide variety of clients, including international corporations and early-stage start-up companies. For clients interested in clinical applications, a cGMP suite is available to manufacture of proteins under the quality standards defined by the U.S. Food and Drug Administration specifically for Phase 1 clinical trials.  

 

By combining the technical capabilities of a university-based pilot-scale CDMO with the expertise of affiliated faculty and researchers, the CBB serves as a trusted partner to biotech startups, vendors for the life science community, pharmaceutical companies, and academic innovators. Our facility supports innovation across multiple sectors, supporting the development and scale-up of protein-based therapeutics, specialty enzymes, reagent proteins, and other next-generation biologics. In addition, CBB plays a key role in bioprocessing workforce development through graduate training and NIH-funded biomanufacturing fellowships, thereby helping to shape the future of the biotech and life sciences industries.  

We Work with a Wide Range of Clients across the Biotech, Life Sciences, and Pharmaceutical Spaces

We welcome clients from diverse industry sectors, including biotech startups seeking scalable biomanufacturing, academic research laboratories advancing translational science, life science vendors supporting basic and applied research worldwide, as well as large multinational pharmaceutical manufacturers and government agencies involved in drug development and public health initiatives. Our services are accessible to clients regardless of geographic location, ensuring professional support for protein production, purification, and bioprocess development. 

How to Start a Service with CBB?

We’re here to support your project every step of the way. Getting started with the Center for Biocatalysis and Bioprocessing (CBB) is simple. Clients can request services by completing our Client Request Form online. After submitting the form, a CBB representative will contact you within 2-3 business days to confirm your request and to schedule an initial consultation.  

 

During this initial consultation, your project requirements will be discussed in a non-confidential manner. CBB will then evaluate whether our facility can meet your specific needs. If so, a Confidential Disclosure Agreement (CDA) template will be provided for your consideration. In parallel, we will share a ballpark estimate of the costs for your project.  
 
Upon execution of the CDA, a more in-depth discussion will be used to provide a more accurate assessment of the costs for CBB’s bioprocessing services. Services can begin once a Master Service Agreement is in place and a Project Ordered is created specifically tailored toward your bioprocessing needs.  
 
Our team will be with you through every step to ensure a smooth and compliant bioprocessing experience.  

Bioprocessing Services

Fermentation, protein purification, & cGMP production for Phase-1 clinical trials

Academic Opportunities

Predoctoral Iowa Biotech Fellowship, CBB & NIH fellowships available

Annual Conference

The CBB hosts an annual conference focusing on innovations in the biocatalytic sciences.

"I worked for CBB since they first started with fermentation in their present location! I had previous experiences running 2000 liter fermenters at Solvay Animal Health. I really enjoyed watching the fermenters being delivered and set up. I worked closely with B. Braun company getting them up and running. The team came together over the next couple years. They have all become very experienced operators in the upstream and downstream processing! Everyone works well together and produces high quality product! I have since retired and miss my coworkers."

CBB Operator Working in the Lab

30 +

Years of Manufacturing Experience
CBB Operator Working in the Lab

265 +

Fellowships Awarded to Students
CBB Operator Working in the Lab

55 +

Associated UI Faculty

News

Maria Spies, Ph.D.

Saturday, November 15, 2025

Tyler J. Woodward

Wednesday, October 15, 2025

Hossein Zare

Wednesday, October 15, 2025

Reza Nejadnik

Wednesday, October 15, 2025

Meet Some of Our Associated Faculty

Office of VP for Research Events

Fort Madison and the War of 1812 with State Archaeologist John Doershuk promotional image

Fort Madison and the War of 1812 with State Archaeologist John Doershuk

Sunday, March 22, 2026 1:30pm to 2:30pm
Fort Madison Riverfront Pavilion
Join us for a presentation that explores Iowa’s only documented War of 1812 site. This talk will feature research and findings from the Office of the State Archaeologist.
"Rural Community-Centered Research: Maternity Care and Why It Matters" — Keynote lecture (in person and virtual) by Katy Kozhimannil, University of Minnesota promotional image

"Rural Community-Centered Research: Maternity Care and Why It Matters" — Keynote lecture (in person and virtual) by Katy Kozhimannil, University of Minnesota

Tuesday, March 24, 2026 7:30am
Virtual

Special Preliminary Event for the Obermann Symposium "Cultivating Rurality: Building Community around Rural Research."

This lecture, co-sponsored by the UI Carver College of Medicine, is designed for a non-clinical audience and will be open to the public. Katy B. Kozhimannil is a Distinguished McKnight University Professor and Co-Director of the University of Minnesota Rural Health Research Center and the University of Minnesota Rural Health Program.

The lecture will take place in Pediatric...

College of Medicine Events

Johnson County Wellness Blood Drive  promotional image

Johnson County Wellness Blood Drive

Wednesday, March 18, 2026 12:00pm to 4:00pm
Johnson County Wellness
The DeGowin Blood Center is hosting a blood drive from 12 P.M. to 4 p.m. on March 18th, 2026, at the Health and Human Services Building!
Fountain Lobby Blood Drive  promotional image

Fountain Lobby Blood Drive

Thursday, March 19, 2026 11:00am to 4:00pm
General Hospital
The DeGowin Blood Center is hosting a blood drive from 11 a.m. to 4 p.m. on March 19th, 2026, at the Fountain Lobby.

College of Pharmacy Events

College of Pharmacy PSET Seminar Series: Bindu Gottam, MS, MBA, RAC

Tuesday, March 24, 2026 11:30am
College of Pharmacy Building

The Department of Pharmaceutical Sciences and Experimental Therapeutics (PSET) in the College of Pharmacy will host a seminar presented by: 

Bindu Gottam, MS, MBA, RAC
Director of Preformulation and Formulation Development
University of Iowa Pharmaceuticals

All are welcome to attend. No pre-registration required.

Building Future Pharmacists: Advancing Experiential Education in the Quad Cities (Preceptor Development Program) promotional image

Building Future Pharmacists: Advancing Experiential Education in the Quad Cities (Preceptor Development Program)

Thursday, March 26, 2026 6:00pm to 8:00pm
Me & Billy Kitchen and Bar

The Department of Pharmacy Practice and Science would like to invite UI College of Pharmacy preceptors to attend "Building Future Pharmacists: Advancing Experiential Education in the Quad Cities."

Program Overview:
Preceptors are invited to a collaborative evening dedicated to preceptor appreciation and expanding experiential learning in the Quad Cities. Come to connect with fellow practitioners, discover ways to support student experiential learning, and explore a new opportunity for a...